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The study found that after 8 weeks of intervention with synbiotic group, the concentration of thyroid-stimulating hormone, levothyroxine dosage and severity score of fatigue were significantly reduced (Talebi et al., 2020)

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The selectivity arises because senescent cells are uniquely dependent on FOXO4-mediated p53 sequestration for survival, while non-senescent cells employ multiple redundant anti-apoptotic mechanisms

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