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3xTg mice have consistently been shown to have impairments in hippocampal-dependent tasks such as Barnes Maze and NOR with memory deficits becoming apparent as early as 4-6 months of age and growing more severe with increasing age 13,59

Tonic somatostatin stimulation unveils delayed GHRH neuron firing patterns To study longer-lasting effects of SST on neuronal activity 18 , GHRH electrical activity was monitored over dozens of minutes

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By neutralizing harmful molecules, it prevents collagen and elastin degradation, maintaining the skin's structural integrity