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These results confirm that tamoxifen induces oxidative damage in breast tumors in vivo and supports our hypothesis that ARE activation could contribute to the development of tamoxifen resistance

Choi et al., J Biol Chem275: 3696

184,394 The mechanism of sepsis-induced ALI/ARDS is complex and multifactorial, involving the release of inflammatory cytokines and disruption of the pulmonary microvascular barrier

Blocking NLRP3, an inflammatory activator, was able to suppress the kidney injury.[ref] Patulin is also known for causing kidney damage

Metabolic profiling by Seahorse assay suggested that melatonin treated ILC2s exhibited decreased rates of basal respiration ( Figure 5P ), decreased spare respiratory capacity ( Figure 5Q ), and both reduced active rates of glycolysis ( Figure 5R ) as well as reduced glycolytic capacity ( Figure 5S )