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In a more recent RCT, the addition of daily oral multivitamins and minerals to the stimulation regimen of patients with unexplained infertility treated with IVF/ICSI did not improve oocyte quality (metaphase II oocytes) or pregnancy rates in these women (194)

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The CesAs terminal C domain is proposed to work in trans with the D- O -Leu-D-Ala peptide as donor and the hydroxy group of the CesB1 PCP-thioester bound L- O -Val, followed by CesB2 PCP-bound L-Val as nucleophilic acceptors 8