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But whenever Sinclair brings up senolytics, he usually mentions both fisetin and quercetin, both of which are potent anti-inflammatory plant-based compounds (polyphenols) that significantly reduce senescent cells in preclinical studies

Exp Mol Med 55(5):939951

"In our clinical trials, Cagrilintide has provided substantial weight loss, in a distinct manner compared to approved obesity medications, and appears well-tolerated," Martin Holst Lange, Novo Nordisk's chief scientific officer and executive vice president of research and development, said in a statement

Biochem Biokhimiia 70:200214 Adam-Vizi V, Chinopoulos C (2006) Bioenergetics and the formation of mitochondrial reactive oxygen species