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The authors of a study investigated the effects of GSH in nine patients with untreated early PD

Some researchers adjust timing or escalation speed based on body weight

Other Dietary Sources Worth Noting While concentrations are considerably lower than in mushrooms, ergothioneine can also be found in: Animal products: Liver (especially kidney and red blood cells contain moderate amounts) These levels reflect the ergothioneine animals consumed from their own diets Legumes: Black beans, kidney beans, and red beans (especially when grown with mycorrhizal fungi) A 2023 study found black beans showed up to 72 times more ergothioneine when grown with beneficial soil fungi [2] Grains and fermented foods: Oat bran and wheat (particularly when cultivated with specific soil fungi) Tempeh, natto, miso, kimchi, and sauerkraut contain small amounts Spirulina contains relatively high amounts compared to other non-fungal sources Typical dietary intake ranges from 5-20 mg per day depending on mushroom consumption patterns

Further corroborating this, a UK-based study found that the protective effect of vegetable consumption against colorectal cancer was primarily confined to individuals with a deficient or intermediate GSTT1 phenotype (61)