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Similar content being viewed by others Introduction The intracellular redox milieu is supported by the thioredoxin system, composed of the flavoenzyme thioredoxin reductase (TrxR, EC 1.8.1.9), NADPH, and its main substrate thioredoxin (Trx)

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Two multicenter Phase I randomized trials to compare the bioequivalence and safety of a generic doxorubicin hydrochloride liposome injection with Doxil or Caelyx in advanced ovarian cancer