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While oral DFP has a risk of hematological toxicity (Ruivard and Lobbes, 2023), oral DFX can cause hepatic and renal toxicity and gastrointestinal bleeding with chronic use (Yusuf et al., 2023)

Class V was reserved for variants with increased activity, but after an initial report (G6PD Hektoen ), none has been found

The study concluded that the glucose caused a significant increase in the oxidative stress markers, lowering the glutathione levels and that this reduction in glutathione was associated with an increase in testosterone

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Initial effects often appear within the first week of consistent use