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With suction from the mouthpiece through the hose, emissions are pulled down through the body, moving through the water in the bowl before inhalation through the hose ( Figure 12.4.2 )

Thicker cigars allow for cooler, gentler smoke due to the looser draw

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Results: As the transfer number advanced, CK5, CK14 and p63 expression was decreased in both explants and BEC from both smokers without COPD and patients with COPD, with a more pronounced decrease in BEC numbers in the COPD group