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While substantial post-ban drops can be observed in small, cherry-picked cities, those putative effects disappear when researchers look at large populations or large numbers of jurisdictions and take into account pre-existing trends

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The low heterogeneity observed in studies on current users (I 2 = 0%) suggests consistent results, while the moderate heterogeneity for former and ever users emphasizes the need for further research to explore the complexities of e-cigarette exposure and its role in COPD development