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E (MNA + /MNAH) = 194 2 mV (Fig

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This can cause the estrogen metabolites to be reabsorbed from the intestines and go back into circulation.[ref] Calcium D-glucarate can suppress the beta-glucuronidase activity in the gut, thus increasing the number of estrogen metabolites that are excreted.[ref] Hormone Replacement Therapy: Hormone replacement therapy (HRT) in menopause is the replacement of naturally declining estrogen and progesterone levels with either synthetic or bioidentical hormones

Starting at 2 mg and escalating slowly is KEY, as the Phase 2 data showed a lower starting dose of 2 mg produced meaningfully fewer GI side effects than jumping in at 4 mg