glutathione for autistic kids Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109) Oxidative Stress Indicated by Nuclear

15 Being a powerful antioxidant, glutathione plays a critical role in several metabolic pathways: DNA and protein synthesis, amino acid transport, enzyme activation, immune system function, scavenging free radicals eg hydrogen peroxide, cofactor in Phase I cytochrome P450 enzyme-mediated detoxification, amino acid translocation across cell membranes, detoxification of xenobiotics, maintenance of sulfhydryl groups of proteins, mitochondrial function and maintenance of mitochondrial DNA, catalysis of exchange reactions and many more

doi:10.1155/2014/698574 11

IUPHAR Database of Receptors and Ion Channels

Cell 167 , 9851000 e1021 (2016)

The protein expression levels of tight junction associated protein-1 (ZO-1), Occludin, inflammatory factors interleukin (IL)-6, IL-1 and tumor necrosis factor (TNF)-, SIRT1, STAT3, p-STAT3, and retinoic acid receptor-related orphan receptor gamma t (RORt) were detected by Western blot