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Figure 2: Changes in A) SOD activity, B) total GSH, C) IL-6 levels in BALF, and D) TNF-alpha levels in BALF across the treatment groups in response to varying doses of GHK-Cu

10.3390/geriatrics10030067 97 ThirupathiA.MarquezeL

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It is known that Down patients suffer from mild to moderate oxidative stress due to the overexpression of the Cu-Zn superoxide dismutase (SOD) gene that is also located on chromosome 21 [62]