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412 Ketamine action on the morphology of astrocytes is mediated through cAMP intracellular signalling: ketamine directly increases cytoplasmic cAMP without activation of metabotropic receptors

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Neurodegeneration also targets the vestibular, pontine, and motor nuclei of the brainstem, as well as subregions of the basal ganglia including the globus pallidus , subthalamic nuclei, and the substantia nigra