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The mesolimbic (reward) dopamine pathway drives the reinforcing effects of tobacco smoking, while the mesocortical (goal-directed) dopamine pathwayincluding the dlPFCis critical for inhibitory control (Wu et al., 2/3 receptor (D 2 R) signaling in dlPFC is associated with cognitive deficits, such as impairments in attention, learning, working memory, and inhibitory control (Arnsten et al., Cigarette smoking has been associated with adverse reproductive outcomes including infertility, subfecundity, early menopause, and menstrual disorders (Department of Health Human Services, A preclinical study has shown that sex steroid hormones are involved in the acquisition of, motivation for, and reinstatement of drug taking
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Key DoseResponse Study in Obstructive Lung Diseases Obstructive lung disease also appears to be affected to a greater extent by smoking duration than intensity
The legal age for buying e-cigarettes in Norway is 18 years
